MedDataToolRivaroxaban granule is a medication used to treat and prevent blood clots in children and young patients, particularly those with certain heart conditions or who have had specific surgeries. It works by blocking a substance in the blood that helps clots form, making it less likely for harmful clots to develop. The medication is taken as an oral suspension, with doses based on the child's weight, starting from 0.8 mg for those weighing around 2.6 kg and going up to a maximum of 20 mg for those weighing 50 kg or more, usually given once or twice a day with food to help absorption. It's important to know that this medication should not be used in children with active bleeding or severe allergic reactions to it. Additionally, if your child is taking other blood thinners like warfarin, special care must be taken when switching between these medications to ensure safety.
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Uses
- treatment of venous thromboembolism (VTE) in pediatric patients. reduction in the risk of recurrent VTE in pediatric patients. thromboprophylaxis in pediatric patients with congenital heart disease after the Fontan procedure.
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Dosage
Pediatric dosing varies by weight; see specific recommendations.
Take doses with food to increase absorption for VTE treatment.
For thromboprophylaxis, doses can be taken with or without food.
Monitor child's weight regularly to adjust dosage as needed.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
bleedingcoughvomitinggastroenteritis
Serious
increased risk of strokespinal/epidural hematoma
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Warnings
⚠ Important warnings
- Premature discontinuation increases risk of thrombotic events.
- Risk of spinal/epidural hematoma with neuraxial anesthesia.
- Not recommended for children under 6 months with certain conditions.
- Monitor for bleeding risks when used with other anticoagulants.
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Drug interactions
- Warfarinincreased bleeding riskCaution
- Enoxaparinincreased bleeding riskCaution
- Aspirinincreased bleeding riskCaution
- Clopidogrelincreased bleeding riskCaution
- Combined P-gp and strong CYP3A inhibitorsincreased bleeding risk.Caution
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Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).