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Rizatriptan

Generic: Rizatriptan Benzoate

Rx only
triptanAlso: MAXALT, MAXALT-MLT✓ FDA-verified
View full FDA label ↗
Rizatriptan is a medication used to treat acute migraines in adults and children aged 6 to 17. It works by targeting specific receptors in the brain to help relieve headache pain. Adults can take a starting dose of either 5 mg or 10 mg, with a maximum of 30 mg in a 24-hour period, while children under 40 kg should take 5 mg, and those 40 kg or more can take 10 mg. It's important to know that this medication should not be used if you have a history of heart problems, such as coronary artery disease. Additionally, if you're taking propranolol, the dose of rizatriptan should be limited to 5 mg, with a maximum of 15 mg in a day.
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Uses

  • acute treatment of migraine with aura. acute treatment of migraine without aura. acute treatment of migraine in pediatric patients aged 6 to 17.
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Dosage

Adults: 5 or 10 mg as a single dose, repeat after 2 hours if needed.
Maximum dose for adults: 30 mg in 24 hours.
Pediatric patients under 40 kg: 5 mg as a single dose.
Pediatric patients 40 kg or more: 10 mg as a single dose.
Adjust dose if taking propranolol.
Always follow your doctor's specific instructions for your dose.
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Side effects

Common

fatiguedizzinesssomnolencepain or pressure sensationschest pain

Serious

tightnessjaw painincrease in blood pressure
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Warnings

⚠ Important warnings

  • Not for patients without a clear migraine diagnosis.
  • Not for hemiplegic or basilar migraine.
  • Not for migraine prevention.
  • Use caution if taking propranolol, as it increases rizatriptan levels.
  • Risk of serotonin syndrome with SSRIs or SNRIs.
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Drug interactions

  • Propranololincreases rizatriptan levelsMonitor
  • Ergot-containing drugsrisk of prolonged vasospasmCaution
  • Other 5-HT 1 agonistsrisk of additive effectsCaution
  • MAO inhibitorsincreases rizatriptan levels.Monitor

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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).