MedDataToolRosuvastatin is a medication used to lower cholesterol and reduce the risk of serious heart problems in adults and children over the age of 7 who have certain cholesterol conditions. It works by blocking a substance your body needs to make cholesterol, which helps lower the bad cholesterol levels in your blood. You take it as a tablet once a day, with a starting dose usually between 5 to 40 mg, depending on your needs, and the maximum dose is 40 mg. It's important to know that this medication should not be taken if you have severe liver problems. Additionally, if you're taking cyclosporine, your doctor will limit your dose of rosuvastatin to no more than 5 mg per day due to potential interactions.
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Uses
- Reduce risk of major cardiovascular events in high-risk adults.
- Lower LDL cholesterol in adults with primary hyperlipidemia.
- Slow progression of atherosclerosis in adults.
- Lower LDL cholesterol in children aged 8 and older with heterozygous familial hypercholesterolemia.
- Lower LDL cholesterol in children aged 7 and older with homozygous familial hypercholesterolemia.
- Treat primary dysbetalipoproteinemia in adults.
- Treat hypertriglyceridemia in adults.
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Dosage
Take orally with or without food, once daily.
Adults: 5 to 40 mg daily.
Children with heterozygous familial hypercholesterolemia: 5 to 20 mg daily.
Children with homozygous familial hypercholesterolemia: 20 mg daily.
Asian patients: Start at 5 mg daily.
Patients with severe renal impairment: Start at 5 mg, max 10 mg daily.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
headachenauseamuscle painfatigueconstipationmuscle breakdown
Serious
liver problemskidney issuesincreased blood sugar levels
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Warnings
⚠ Important warnings
- Risk of muscle problems like myopathy and rhabdomyolysis.
- Monitor liver function due to potential liver damage.
- Increased risk of diabetes.
- Use caution in patients with severe kidney impairment.
- Avoid use with certain medications that increase muscle risk.
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Drug interactions
- Cyclosporineincreases rosuvastatin levels significantlyMonitor
- Gemfibrozilavoid use due to increased muscle riskAvoid
- Teriflunomidedo not exceed 10 mg dailyAvoid
- Enasidenibdo not exceed 10 mg dailyAvoid
- Capmatinibdo not exceed 10 mg dailyAvoid
- Fostamatinibdo not exceed 20 mg dailyAvoid
Ask about this drug
Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).