MedDataToolSeroquel XR is a medication used to treat conditions like schizophrenia, bipolar disorder, and major depressive disorder when combined with other antidepressants. It works by balancing certain chemicals in the brain that affect mood and behavior. You take it as a tablet, usually once a day in the evening, starting with a dose of 300 mg for adults with schizophrenia or bipolar disorder, and it can go up to a maximum of 800 mg. It's important to know that Seroquel XR should not be taken if you have a known allergy to it or its ingredients. Additionally, if you're taking strong medications that affect liver enzymes, like ketoconazole, your doctor may need to adjust your dose significantly.
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Uses
- Schizophrenia.
- Bipolar I disorder, manic or mixed episodes.
- Bipolar disorder, depressive episodes.
- Major depressive disorder, adjunctive therapy with antidepressants.
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Dosage
Adults with schizophrenia: start at 300 mg, increase to 400-800 mg daily.
Adults with bipolar I disorder: start at 300 mg, increase to 400-800 mg daily.
Children (10-17 years) with bipolar I disorder: start at 50 mg, increase to 400-600 mg daily.
Take once daily, preferably in the evening, with or without a light meal.
Elderly patients may need a lower starting dose and careful monitoring.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
somnolencedry mouthconstipationdizzinessincreased appetiteincreased mortality in elderly with dementia-related psychosis
Serious
suicidal thoughts in young adults
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Warnings
⚠ Important warnings
- Increased mortality in elderly patients with dementia-related psychosis.
- Risk of suicidal thoughts and behaviors in children and young adults.
- Use caution in elderly and those with liver impairment.
- Not approved for patients under 10 years old.
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Drug interactions
- Ketoconazolereduce quetiapine dose to one-sixthCaution
- Phenytoinincrease quetiapine dose up to five-foldCaution
- Divalproexmay affect quetiapine levelsCaution
- Alcoholmay enhance cognitive and motor effects.Caution
Ask about this drug
Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).