MedDataToolSertraline is a medication used to treat conditions like major depressive disorder, obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, and social anxiety disorder. It works by increasing the levels of serotonin, a chemical in the brain that helps improve mood and reduce anxiety. You typically take it as a tablet once a day, starting at a dose of 50 mg, which can be increased to a maximum of 200 mg if needed. It's important to know that sertraline should not be taken with certain antidepressants called MAOIs, as this can lead to serious side effects. Additionally, if you have liver problems, you may need a lower dose or less frequent dosing.
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Uses
- Major Depressive Disorder.
- Obsessive-Compulsive Disorder (OCD).
- Panic Disorder.
- Posttraumatic Stress Disorder (PTSD).
- Premenstrual Dysphoric Disorder (PMDD).
- Social Anxiety Disorder.
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Dosage
Adults: Start with 50 mg daily, can increase to 200 mg.
Children (OCD): Start with 25 mg daily for ages 6-12, 50 mg for ages 13-17.
Elderly: Use caution; may require lower doses.
Liver impairment: Use lower or less frequent doses.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
Nauseadiarrheadry mouthdizzinessinsomnia
Serious
Suicidal thoughtsserotonin syndromesevere allergic reactions
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Warnings
⚠ Important warnings
- Increased risk of suicidal thoughts in young adults.
- Monitor for worsening depression or unusual behavior.
- Not approved for pediatric major depressive disorder.
- Avoid use with MAOIs to prevent serious interactions.
- Use caution in patients with liver or kidney issues.
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Drug interactions
- Warfarinmay increase bleeding riskCaution
- Cimetidineincreases sertraline levelsMonitor
- Lithiummonitor levels closelyMonitor
- Pimozidemay increase pimozide levelsCaution
- Alcoholnot recommended with sertraline.Caution
Ask about this drug
Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).