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Tadalafil

Rx only
PDE5 inhibitor✓ FDA-verified
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Tadalafil is a medication used to treat erectile dysfunction (ED) and the symptoms of benign prostatic hyperplasia (BPH), which is an enlarged prostate. It works by increasing blood flow to the penis during sexual stimulation, helping to achieve and maintain an erection. Tadalafil can be taken as needed, starting with a dose of 10 mg before sexual activity, with a maximum of 20 mg, or as a daily dose of 2.5 mg to 5 mg for ongoing treatment. It is important to know that tadalafil should not be taken with any form of nitrates, as this can cause a dangerous drop in blood pressure. Additionally, if you have kidney problems, your doctor may need to adjust your dose accordingly.

Uses

  • erectile dysfunction (ED). benign prostatic hyperplasia (BPH).
  • ED and BPH symptoms.

Dosage

10 mg as needed before sexual activity, max once daily. 2.5 mg once daily for ED, may increase to 5 mg. 5 mg once daily for BPH, taken at the same time each day. 5 mg once daily for ED and BPH, taken at the same time each day.
Do not split tablets; can be taken with or without food.
Always follow your doctor's specific instructions for your dose.

Side effects

Common

headachedyspepsiaback painmyalgianasal congestionflushinglimb painsudden hearing loss

Serious

vision changespriapismcardiovascular events
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Warnings

⚠ Important warnings

  • Do not use with nitrates.
  • Caution with alpha-blockers; may lower blood pressure.
  • Not recommended for severe liver impairment.
  • Use with caution in patients with renal impairment.
  • Consult doctor if experiencing severe side effects.

Drug interactions

  • Nitratescan cause severe low blood pressureCaution
  • Alpha-blockersmay increase blood pressure lowering effectsCaution
  • CYP3A4 inhibitors (e.g., ketoconazole)increases tadalafil exposureMonitor
  • CYP3A4 inducers (e.g., rifampin)decreases tadalafil exposureCaution
  • Alcoholmay increase blood pressure lowering effectsCaution

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Answers pulled from the FDA label only.

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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).