MedDataToolTramadol is a medication used to manage severe and persistent pain when other treatments are not effective. It works by binding to certain receptors in the brain to help reduce the feeling of pain and also affects chemicals that influence mood and pain perception. You will take it as a tablet once a day, starting with a dose of 100 mg, and you should not exceed 300 mg per day. It's important to know that tramadol can be addictive and should be used carefully, especially if you have a history of substance use disorder. Additionally, avoid taking tramadol with monoamine oxidase inhibitors (MAOIs), as this combination can lead to serious side effects.
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Uses
- Severe and persistent pain that requires an opioid analgesic.
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Dosage
Take 100 mg once daily at the same time each day.
Adjust dose based on individual pain needs and tolerance.
Do not exceed 300 mg per day.
Take whole with liquid; do not crush or chew.
Reassess need for medication regularly.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
dizzinessconstipationnauseaheadachedrowsinessflushingitchingvomitinginsomniadry mouthaddiction
Serious
respiratory depressionseizuresserotonin syndromewithdrawal symptoms
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Warnings
⚠ Important warnings
- Risk of addiction, abuse, and misuse.
- Can cause life-threatening respiratory depression.
- Accidental ingestion can be fatal, especially in children.
- Avoid use with benzodiazepines or other CNS depressants.
- Not for children under 12 or post-tonsil/adenoid surgery.
- Monitor for signs of overdose and withdrawal.
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Drug interactions
- CYP2D6 inhibitorsmay increase tramadol levels and decrease active metaboliteCaution
- CYP3A4 inhibitorsmay increase tramadol levels and risk of serious side effectsCaution
- CYP3A4 inducersmay decrease tramadol effectiveness and cause withdrawalCaution
- Benzodiazepinesincreases risk of sedation and respiratory depressionMonitor
- Serotonergic drugsrisk of serotonin syndrome.Caution
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Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).