MedDataToolValacyclovir is an antiviral medication used to treat conditions like cold sores, genital herpes, and shingles. It works by stopping the virus from multiplying in your body, helping to reduce symptoms and prevent outbreaks. You can take it as a tablet, usually starting with a dose of 1 gram twice a day for 10 days for initial genital herpes, and the maximum dose can vary depending on the condition being treated. It's important to know that if you've had a serious allergic reaction to valacyclovir or similar medications like acyclovir, you should not take it. Additionally, if you are taking medications that affect kidney function, such as cimetidine, you may need a dose adjustment.
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Uses
- Cold Sores (Herpes Labialis).
- Genital Herpes Treatment.
- Genital Herpes Suppression.
- Reduction of Transmission of Genital Herpes.
- Herpes Zoster (Shingles).
- Chickenpox in pediatric patients.
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Dosage
Cold Sores: 2 grams every 12 hours for 1 day.
Genital Herpes Initial Episode: 1 gram twice daily for 10 days.
Genital Herpes Recurrent Episodes: 500 mg twice daily for 3 days.
Suppressive Therapy: 1 gram once daily for immunocompetent patients.
Herpes Zoster: 1 gram 3 times daily for 7 days.
Chickenpox (ages 2 to <18 years): 20 mg/kg 3 times daily for 5 days.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
headachenauseaabdominal pain
Serious
acute renal failurecentral nervous system effectssevere skin reactions
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Warnings
⚠ Important warnings
- Not established for immunocompromised patients except HIV-1 suppression.
- Use caution in patients with renal impairment.
- Contraindicated in patients with hypersensitivity to valacyclovir.
- Safer sex practices should be used with suppressive therapy.
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Drug interactions
- Cimetidineincreases acyclovir levelsMonitor
- Probenecidincreases acyclovir levelsMonitor
- Thiazide Diureticsno significant effect on acyclovirCaution
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Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).