MedDataToolVarenicline is a medication that helps people quit smoking by reducing cravings and withdrawal symptoms. It works by partially activating the same brain receptors that nicotine does, which helps lessen the urge to smoke while also blocking nicotine from attaching to those receptors. You should start taking it one week before your planned quit date, beginning with 0.5 mg once daily for the first three days, then 0.5 mg twice daily for the next four days, and finally 1 mg twice daily for the remaining 12 weeks. It's important to note that varenicline should not be used if you have a history of serious allergic reactions to it. Additionally, if you're taking medications that affect kidney function, such as cimetidine, you may need to be cautious as they can increase the levels of varenicline in your body.
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Uses
- Aid to smoking cessation.
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Dosage
Start taking varenicline one week before quitting smoking.
Take 0.5 mg once daily for the first 3 days.
Take 0.5 mg twice daily from days 4 to 7.
Take 1 mg twice daily from day 8 for a total of 12 weeks.
Consider an additional 12 weeks for those who successfully quit.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
nauseaabnormal dreamsconstipationflatulencevomitingneuropsychiatric events
Serious
seizuresaccidental injurycardiovascular events
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Warnings
⚠ Important warnings
- May cause neuropsychiatric events including suicidal thoughts.
- Risk of seizures, especially in those with a history.
- Avoid alcohol as it may increase side effects.
- Monitor for accidental injuries.
- Patients with severe kidney issues should start with a lower dose.
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Drug interactions
- Bupropionsafety not established with combinationCaution
- Transdermal nicotinehigher adverse reaction rates when combined.Caution
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Answers pulled from the FDA label only.
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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).