MedDataToolVenlafaxine is a medication used to treat major depressive disorder, helping to improve mood and reduce feelings of sadness. It works by increasing the levels of certain chemicals in the brain that are involved in mood regulation. You typically take it as a tablet, starting with a dose of 75 mg per day, which can be increased to a maximum of 375 mg per day if needed, and it's best taken with food. One important warning is that it may increase the risk of suicidal thoughts or behaviors, especially in younger patients. Additionally, you should not take venlafaxine if you are currently using monoamine oxidase inhibitors (MAOIs), as this combination can lead to serious side effects.
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Uses
- major depressive disorder.
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Dosage
Start with 75 mg/day, taken in two or three doses.
Can increase to 150 mg/day based on tolerance.
May go up to 225 mg/day if needed.
For severe cases, doses may reach 375 mg/day.
Always take with food.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
nauseaheadachedizzinessdry mouthinsomniasweatingincreased blood pressure
Serious
suicidal thoughtsserotonin syndrome
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Warnings
⚠ Important warnings
- Increased risk of suicidal thoughts in young adults.
- Monitor for worsening depression or unusual behavior.
- Not approved for use in children.
- Avoid use with MAOIs like linezolid or methylene blue.
- May cause sustained high blood pressure.
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Drug interactions
- Cimetidineincreases venlafaxine levelsMonitor
- Diazepamno significant interactionCaution
- Haloperidolincreases haloperidol levelsMonitor
- Lithiumno significant interactionCaution
- Warfarinmonitor for increased bleeding risk.Monitor
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Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).