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Verapamil

Generic: Verapamil Hydrochloride

Rx only
Calcium channel blocker✓ FDA-verified
View full FDA label ↗
Verapamil is a medication used to treat conditions like angina (chest pain), certain heart rhythm problems, and high blood pressure. It works by relaxing the blood vessels and slowing down the heart rate, which helps improve blood flow and reduce the heart's workload. You typically take it in tablet form, starting with a dose of 80 mg three times a day, and the maximum dose should not exceed 480 mg per day. A key warning is that it should not be used in patients with severe heart failure or very low blood pressure. Additionally, if you are taking beta-blockers, you should be cautious, as this combination can lead to serious heart issues.
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Uses

  • Angina at rest.
  • Chronic stable angina.
  • Atrial flutter.
  • Atrial fibrillation.
  • Essential hypertension.
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Dosage

80 mg to 120 mg three times a day for angina. 240 mg to 320 mg per day for atrial flutter or fibrillation.
Initial dose for hypertension is 80 mg three times a day.
Dosage may be adjusted based on response.
Always follow your doctor's specific instructions for your dose.
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Side effects

Common

constipationdizzinessheadachenauseafatigue

Serious

heart failurehypotensionelevated liver enzymesAV block
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Warnings

⚠ Important warnings

  • Avoid in severe left ventricular dysfunction.
  • Risk of hypotension and dizziness.
  • Monitor liver function during treatment.
  • Use caution in patients with atrioventricular block.
  • Avoid in patients with accessory bypass tract.
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Drug interactions

  • Erythromycinincreases verapamil levelsMonitor
  • Rifampindecreases verapamil levelsCaution
  • Digoxinmay increase digoxin levelsCaution
  • Beta-blockersmay enhance heart rate effectsCaution
  • Grapefruit juiceincreases verapamil levelsMonitor

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Answers pulled from the FDA label only.

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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).