MedDataToolWarfarin sodium is a medication used to prevent and treat blood clots in conditions like deep vein thrombosis, pulmonary embolism, and certain heart issues. It works by blocking the action of vitamin K, which is necessary for making blood-clotting factors, thereby helping to reduce the risk of clots forming. You typically take it as a tablet once daily, starting with a dose of 2 to 5 mg, with maintenance doses ranging from 2 to 10 mg based on your individual needs. It's very important to note that warfarin should not be taken during pregnancy, as it can harm the fetus. Additionally, if you are taking heparin, a common blood thinner, your doctor will need to monitor your blood closely to ensure the right balance of anticoagulation.
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Uses
- Venous thrombosis.
- Pulmonary embolism.
- Thromboembolic complications from atrial fibrillation.
- Cardiac valve replacement.
- Reduction in risk of death after myocardial infarction.
- Prevention of stroke.
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Dosage
Individualized dosing based on INR response.
Initial dose usually 2 to 5 mg once daily.
Maintain INR between 2 to 3 for most conditions.
Monitor INR daily until stable, then every 1 to 4 weeks.
Adjust dose based on INR and specific condition.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
NauseaVomitingDiarrheaRash
Serious
HemorrhageTissue necrosis
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Warnings
⚠ Important warnings
- Risk of major or fatal bleeding.
- Monitor INR regularly.
- Be cautious with dietary changes.
- Consult about all medications taken.
- Use caution in elderly patients.
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Drug interactions
- Heparinincreases INR riskMonitor
- Aspirinincreases bleeding riskMonitor
- Antibioticsmay affect INRCaution
- Antifungalsmay affect INRCaution
- Ginkgo bilobaincreases bleeding riskMonitor
- John’s wortdecreases warfarin effectCaution
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Answers pulled from the FDA label only.
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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).