MedDataToolXarelto is a medication used to prevent blood clots and reduce the risk of stroke in people with certain heart conditions, as well as to treat conditions like deep vein thrombosis and pulmonary embolism. It works by blocking a specific protein in the blood that helps clots form, making it harder for clots to develop. You typically take it as a tablet, with doses ranging from 10 mg to 20 mg, depending on your condition, and it’s important to take it with food to help your body absorb it better. One key warning is that Xarelto should not be taken if you have active bleeding issues, as it can increase the risk of serious bleeding. Additionally, if you are taking other blood thinners like warfarin, be cautious, as this can increase the risk of bleeding complications.
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Uses
- Reduce risk of stroke in nonvalvular atrial fibrillation.
- Treatment of deep vein thrombosis (DVT).
- Treatment of pulmonary embolism (PE).
- Reduce risk of recurrence of DVT or PE.
- Prophylaxis of DVT after knee or hip replacement surgery.
- Prophylaxis of venous thromboembolism in acutely ill medical patients.
- Reduce risk of major cardiovascular events in coronary artery disease.
- Reduce risk of major thrombotic vascular events in peripheral artery disease.
- Treatment of venous thromboembolism in pediatric patients.
- Thromboprophylaxis in pediatric patients with congenital heart disease after Fontan procedure.
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Dosage
15 mg twice daily for 21 days, then 20 mg once daily for DVT/PE. 10 mg once daily for DVT prophylaxis after hip or knee surgery. 10 mg once daily for venous thromboembolism prophylaxis in acutely ill patients. 2.5 mg twice daily with aspirin for CAD or PAD.
Pediatric dosing varies by weight and age.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
BleedingCoughVomitingGastroenteritisSpinal/epidural hematoma
Serious
Increased risk of stroke after discontinuation
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Warnings
⚠ Important warnings
- Premature discontinuation increases risk of thrombotic events.
- Risk of spinal/epidural hematoma with neuraxial anesthesia.
- Avoid use in patients with severe renal impairment.
- Monitor for bleeding risk with other anticoagulants.
- Consider risks before spinal procedures in anticoagulated patients.
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Drug interactions
- Warfarinincreased bleeding riskCaution
- Aspirinincreased bleeding riskCaution
- Clopidogrelincreased bleeding riskCaution
- Erythromycinincreased rivaroxaban exposureCaution
- Ketoconazoleincreased rivaroxaban exposureCaution
- Rifampindecreased rivaroxaban exposureCaution
Ask about this drug
Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).