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Zanamivir

Rx only
Neuraminidase InhibitorAlso: RELENZA✓ FDA-verified
View full FDA label ↗
Zanamivir is a medication used to treat uncomplicated influenza caused by type A and B viruses in patients aged 7 years and older who have had symptoms for no more than 2 days, and it can also help prevent influenza in people aged 5 years and older. It works by blocking a specific enzyme that the virus needs to spread in the body. The medication is taken as an inhaled powder, with a starting dose of 10 mg twice daily for 5 days when treating influenza, or 10 mg once daily for 10 days in a household setting for prevention. It is important to note that zanamivir is not recommended for individuals with underlying airway diseases, such as asthma, due to the risk of serious breathing problems. Additionally, if you are using an inhaled bronchodilator, you should take that medication before using zanamivir.

Uses

  • Treatment of influenza type A.
  • Treatment of influenza type B.
  • Prophylaxis of influenza in patients aged 5 years and older.

Dosage

Adults and children 7 years and older: 10 mg twice daily for 5 days for treatment.
Children aged 5 years and older: 10 mg once daily for 10 days for prophylaxis in a household setting.
For community outbreaks: 10 mg once daily for 28 days.
Doses should be taken at the same time each day.
Always follow your doctor's specific instructions for your dose.

Side effects

Common

sinusitisdizzinessfeverchillsmuscle painbronchospasm

Serious

allergic reactionsseizurespsychiatric symptoms
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Warnings

⚠ Important warnings

  • Not recommended for individuals with underlying airways disease.
  • Not proven effective for treatment in individuals with underlying airways disease.
  • Not a substitute for annual influenza vaccination.
  • Use with caution in patients with renal impairment.

Drug interactions

  • Live attenuated influenza vaccinedo not use within 2 weeks before or 48 hours after RELENZA.Avoid

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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).