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Zyprexa Relprevv

Generic: Olanzapine Pamoate

Rx only
Atypical antipsychotic✓ FDA-verified
View full FDA label ↗
Zyprexa Relprevv is a long-acting medication used to treat schizophrenia, a mental health condition that affects how a person thinks, feels, and behaves. It works by helping to balance certain chemicals in the brain that can be out of balance in people with this condition. The medication is given as an injection into the muscle, typically every 2 to 4 weeks, with a starting dose of 150 mg every 4 weeks and a maximum dose of 405 mg every 4 weeks. One important warning is that patients need to be monitored for at least 3 hours after each injection for potential sedation or confusion. Additionally, if you are taking oral olanzapine, your doctor may need to adjust your dosage when switching to Zyprexa Relprevv.

Uses

  • Schizophrenia.

Dosage

150 mg every 2 weeks or 300 mg every 4 weeks for maintenance.
Doses above 405 mg every 4 weeks or 300 mg every 2 weeks have not been studied.
Administered by a healthcare professional via deep intramuscular injection.
Establish tolerability with oral olanzapine before starting ZYPREXA RELPREVV.
Always follow your doctor's specific instructions for your dose.

Side effects

Common

Common side effects include headachesedationweight gaincoughand diarrhea

Serious

Serious side effects may include severe sedationdeliriumand increased risk of death in elderly patients
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Warnings

⚠ Important warnings

  • Patients must be observed for at least 3 hours after injection for sedation or delirium.
  • Not approved for treating dementia-related psychosis in elderly patients.
  • ZYPREXA RELPREVV is available only through a restricted distribution program.

Drug interactions

  • Diazepammay increase risk of low blood pressureCaution
  • Alcoholmay enhance low blood pressure effectsCaution
  • Carbamazepineincreases clearance of olanzapineMonitor
  • Fluvoxaminemay increase olanzapine levels.Caution

Ask about this drug

Answers pulled from the FDA label only.

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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).