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Baclofen

Rx only
GABA agonist✓ FDA-verified
View full FDA label ↗
Baclofen is a medication used to help relieve muscle stiffness and spasms caused by conditions like multiple sclerosis and spinal cord injuries. It works by calming the nerves in the spinal cord, which helps reduce muscle tightness. You take it in tablet form, starting with a low dose of 5 mg three times a day, and the dose can be gradually increased up to a maximum of 80 mg per day. It's important to know that if you stop taking baclofen, you should do so gradually to avoid serious withdrawal symptoms. Additionally, if you have kidney problems, you may need a lower dose, as the medication is mainly cleared from the body through the kidneys.

Uses

  • Spasticity from multiple sclerosis.
  • Flexor spasms.
  • Pain associated with spasticity.
  • Clonus.
  • Muscular rigidity.
  • Spinal cord injuries.
  • Other spinal cord diseases.

Dosage

Start with a low dose and increase gradually.
Typical effective dose is between 40-80 mg daily.
Follow a titration schedule starting at 5 mg three times a day.
Maximum daily dose should not exceed 80 mg.
Always follow your doctor's specific instructions for your dose.

Side effects

Common

drowsinessdizzinessweaknessfatigueconfusionGastrointestinal issues: nauseaconstipationCardiovascular: hypotensionchest painGenitourinary: urinary frequencyimpotence

Serious

hallucinationsseizuresmuscle pain
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Warnings

⚠ Important warnings

  • Withdrawal symptoms may occur in newborns if taken during pregnancy.
  • Abrupt withdrawal can cause hallucinations and seizures.
  • Use with caution in patients with kidney issues.
  • Not recommended for stroke patients.
  • Use during pregnancy only if benefits outweigh risks.

Ask about this drug

Answers pulled from the FDA label only.

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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).