MedDataToolChlorthalidone is a medication used to help manage high blood pressure and reduce swelling caused by conditions like heart failure or liver disease. It works by helping your body get rid of extra salt and water, which lowers blood pressure and reduces swelling. You typically take it as a pill once a day in the morning, starting with a dose of 25 mg, which can be increased to a maximum of 100 mg if needed. It’s important to be cautious if you have severe kidney problems, as this medication may not be safe for you. Additionally, be aware that taking chlorthalidone with alcohol or narcotics can increase the risk of low blood pressure.
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Uses
- Hypertension.
- Edema associated with congestive heart failure.
- Edema due to hepatic cirrhosis.
- Edema from corticosteroid therapy.
- Edema from estrogen therapy.
- Edema due to nephrotic syndrome.
- Edema from acute glomerulonephritis.
- Edema in chronic renal failure.
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Dosage
Start with 25 mg once daily for hypertension.
May increase to 50 mg if needed.
For edema, start with 50 to 100 mg daily.
Some may need 150 to 200 mg at intervals.
Maintenance doses may be lower than initial doses.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
NauseaVomitingDizzinessHeadacheWeaknessRashThrombocytopeniaHyperglycemia
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Warnings
⚠ Important warnings
- Use with caution in severe renal disease.
- May cause azotemia in renal patients.
- Caution in patients with liver disease.
- Sensitivity reactions may occur in allergic patients.
- May exacerbate systemic lupus erythematosus.
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Drug interactions
- Digitalismay influence serum electrolytesCaution
- Other antihypertensive drugsmay enhance effectsCaution
- Insulinmay change requirementsCaution
- Oral hypoglycemic agentsmay require higher dosesCaution
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Answers pulled from the FDA label only.
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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).