MedDataToolFenofibrate is a medication used to help lower bad cholesterol and triglycerides while increasing good cholesterol in adults with high cholesterol or severe triglyceride levels. It works by helping your body break down fats and remove them from the bloodstream. You typically take it as a tablet once a day, starting with a dose of 160 mg, but if you have severe triglyceride issues, your doctor might start you on a lower dose between 54 mg and 160 mg, with a maximum of 160 mg daily. It's important to know that fenofibrate should not be taken if you have severe kidney problems. Additionally, if you are taking certain diabetes medications like glimepiride, fenofibrate can increase its levels in your body, so your doctor may need to adjust your doses.
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Uses
- Primary hypercholesterolemia.
- Mixed dyslipidemia.
- Severe hypertriglyceridemia.
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Dosage
Initial dose for primary hypercholesterolemia is 160 mg once daily.
Initial dose for severe hypertriglyceridemia is 54 to 160 mg once daily.
Take fenofibrate with meals to improve absorption.
Monitor lipid levels and adjust dosage as needed.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
Abdominal painBack painHeadacheNauseaPancreatitisBlood clots
Serious
Increased liver testsSerious liver damageAllergic reactions
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Warnings
⚠ Important warnings
- Not shown to reduce heart disease in type 2 diabetes patients.
- Use with caution in patients with liver issues.
- Risk of pancreatitis with high triglycerides.
- Monitor kidney function in elderly patients.
- Avoid use in severe renal impairment.
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Drug interactions
- Coumarin anticoagulantsincreased bleeding riskCaution
- Immunosuppressantsrisk of kidney damageCaution
- Bile acid resinsmay affect absorptionCaution
- Colchicinerisk of muscle problemsCaution
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Answers pulled from the FDA label only.
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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).