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Fluphenazine

Generic: Fluphenazine Hydrochloride

Rx only
Antipsychotic✓ FDA-verified
View full FDA label ↗
Fluphenazine is a medication used to help manage symptoms of psychotic disorders. It works by affecting certain chemicals in the brain to help improve mood and behavior. You can take it in pill form, usually starting with a dose between 2.5 to 10 mg per day, divided into smaller doses throughout the day, and it may be increased if needed, with a maximum daily dose of 40 mg. A key warning is that it is not approved for treating elderly patients with dementia-related psychosis due to an increased risk of death. Additionally, if you're taking alcohol or other central nervous system depressants, be cautious, as they can enhance the effects of fluphenazine.

Uses

  • Psychotic disorders.

Dosage

Initial dose for adults: 2.5 to 10 mg daily, divided into doses every 6 to 8 hours.
Therapeutic effect often achieved with doses under 20 mg daily.
For severe cases, daily doses may go up to 40 mg.
For elderly patients, starting dose is 1 to 2.5 mg daily.
Always follow your doctor's specific instructions for your dose.

Side effects

Common

Drowsinessdry mouthheadacheblurred visionTardive dyskinesia

Serious

neuroleptic malignant syndromesevere muscle rigidity
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Warnings

⚠ Important warnings

  • Increased risk of death in elderly patients with dementia-related psychosis.
  • Risk of tardive dyskinesia with long-term use.
  • Potential for neuroleptic malignant syndrome, which can be fatal.
  • Use caution in patients with heart or kidney issues.
  • Not approved for dementia-related psychosis.

Drug interactions

  • Alcoholmay enhance sedative effectsCaution
  • Antiparkinsonian drugscan help control side effects.Caution

Ask about this drug

Answers pulled from the FDA label only.

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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).