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Haloperidol Decanoate

Rx only
Antipsychotic✓ FDA-verified
View full FDA label ↗
Haloperidol decanoate is a long-acting injection used to treat schizophrenia in patients who need ongoing antipsychotic therapy. It works by blocking certain receptors in the brain that are involved in mood and behavior. The medication is given as a deep injection into the muscle, typically once a month, with a starting dose based on previous treatments, usually not exceeding 100 mg for the first dose. It's important to know that this medication should not be used in patients with Parkinson's disease, as it can worsen their symptoms. Additionally, if you are taking lithium, you should be closely monitored, as combining these two can lead to serious side effects.
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Uses

  • Schizophrenia.
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Dosage

Administered by deep intramuscular injection.
Use a 21 gauge needle for injection.
Maximum volume per injection site is 3 mL.
Initial dose based on patient's history and response.
Usually given monthly or every 4 weeks.
Always follow your doctor's specific instructions for your dose.
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Side effects

Common

ParkinsonismakinesiaakathisiatremorNeuroleptic Malignant Syndrome

Serious

oculogyric crisistardive dyskinesiahypersensitivity reactions
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Warnings

⚠ Important warnings

  • Increased mortality in elderly patients with dementia-related psychosis.
  • Do not administer intravenously.
  • Risk of cardiovascular effects like sudden death.
  • Caution in patients with cerebrovascular risk factors.
  • Contraindicated in patients with Parkinson's Disease or Dementia with Lewy Bodies.
  • Monitor closely if combined with lithium.
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Drug interactions

  • Lithiumrisk of neurological toxicity.Caution

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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).