MedDataToolMetoprolol is a medication used to treat high blood pressure, angina (chest pain), and to reduce the risk of death after a heart attack. It works by blocking certain signals in the heart, which helps to lower heart rate and blood pressure, making it easier for the heart to pump blood. You typically take it as a tablet once a day, starting with a dose of 100 mg, which can be adjusted up to a maximum of 450 mg per day based on your needs. It's important to know that metoprolol should not be taken if you have severe slow heart rate or certain heart conditions. Additionally, if you're taking drugs that affect the liver enzyme CYP2D6, like quinidine, it can significantly increase the levels of metoprolol in your body, so be sure to discuss this with your doctor.
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Uses
- Hypertension.
- Angina Pectoris.
- Myocardial Infarction.
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Dosage
Take once daily with food or after a meal.
Hypertension: Start with 100 mg daily, adjust as needed.
Angina Pectoris: Start with 100 mg daily, in two doses.
Myocardial Infarction: Follow intravenous dosing instructions.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
tirednessdizzinessdepressionshortness of breathbradycardiahypotensiondiarrhearashworsening angina or myocardial infarctionAV block
Serious
worsening heart failure
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Warnings
⚠ Important warnings
- May worsen angina or heart failure.
- Contraindicated in severe peripheral circulatory disorders.
- Monitor for hypotension with catecholamine depleting drugs.
- May reduce response to epinephrine in allergic reactions.
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Drug interactions
- Catecholamine-depleting drugsmay cause hypotensionCaution
- Epinephrinemay be less effectiveCaution
- CYP2D6 Inhibitorsincrease metoprolol concentrationCaution
- Digitalis glycosidesrisk of bradycardiaCaution
- Clonidinemay cause rebound hypertension.Caution
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Answers pulled from the FDA label only.
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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).