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Metoprolol Succinate

Generic: Metoprolol Succinate Er Tablets

Rx only
Beta-blocker✓ FDA-verified
View full FDA label ↗
Metoprolol succinate is a medication used to treat high blood pressure, angina (chest pain), and heart failure. It works by blocking certain signals in the heart, which helps to lower heart rate and blood pressure, making it easier for the heart to pump blood. You take it as a pill once a day, starting with a dose of 25 mg to 100 mg for high blood pressure, 100 mg for angina, or 12.5 mg to 25 mg for heart failure, with a maximum dose of 400 mg per day. It's important to know that this medication should not be taken if you have severe slow heart rate or certain heart block conditions. Additionally, if you're taking drugs that affect the liver enzyme CYP2D6, such as quinidine, it can increase the levels of metoprolol in your body, so be sure to discuss this with your doctor.
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Uses

  • Hypertension.
  • Angina Pectoris.
  • Heart Failure.
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Dosage

Hypertension: 25 mg to 100 mg once daily.
Angina Pectoris: 100 mg once daily.
Heart Failure: 12.5 mg or 25 mg once daily.
Adjust dosage at weekly intervals as needed.
Always follow your doctor's specific instructions for your dose.
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Side effects

Common

tirednessdizzinessdepressiondiarrheashortness of breathbradycardiahypotensionrashworsening AV block

Serious

worsening angina or heart failure
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Warnings

⚠ Important warnings

  • Do not use if you have severe heart block.
  • May worsen heart failure symptoms.
  • Monitor for hypotension and bradycardia.
  • Caution with catecholamine-depleting drugs.
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Drug interactions

  • CYP2D6 Inhibitorsmay increase metoprolol levelsCaution
  • Clonidinemay cause rebound hypertension if withdrawn too quicklyCaution
  • Digitalisincreases risk of bradycardiaMonitor
  • Calcium Channel Blockersmay slow heart rate.Caution

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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).