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Metoprolol Succinate Er

Generic: Metoprolol Succinate Er Tablets

Rx only
beta-blockerAlso: Metoprolol Succinate✓ FDA-verified
View full FDA label ↗
Metoprolol succinate is a medication used to treat high blood pressure, angina (chest pain), and heart failure. It works by blocking certain signals in the heart, which helps to lower heart rate and blood pressure, making it easier for the heart to pump blood. You take it as an extended-release tablet once a day, starting with a dose of 25 mg to 100 mg for high blood pressure, 100 mg for angina, or 12.5 mg to 25 mg for heart failure, with a maximum dose of up to 400 mg daily depending on your condition. It's important to know that this medication should not be taken if you have severe bradycardia (a very slow heart rate) or certain heart block conditions. Additionally, if you are taking drugs that affect the CYP2D6 enzyme, like quinidine, it can increase the levels of metoprolol in your body, so be sure to discuss any other medications with your doctor.
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Uses

  • Hypertension.
  • Angina Pectoris.
  • Heart Failure.
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Dosage

Hypertension: 25 mg to 100 mg once daily.
Angina Pectoris: 100 mg once daily.
Heart Failure: 12.5 mg or 25 mg once daily.
Adjust dosage as needed and tolerated.
Always follow your doctor's specific instructions for your dose.
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Side effects

Common

tirednessdizzinessdepressionshortness of breathbradycardiahypotensiondiarrhearashworsening AV block

Serious

worsening angina or heart failure
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Warnings

⚠ Important warnings

  • Do not use if you have severe heart block.
  • May worsen angina or heart failure.
  • Monitor for hypotension and bradycardia.
  • Caution with catecholamine-depleting drugs.
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Drug interactions

  • CYP2D6 Inhibitorsmay increase metoprolol concentrationCaution
  • Clonidinemay worsen rebound hypertension if stopped suddenlyCaution
  • Digitalisincreases risk of bradycardiaMonitor
  • Calcium Channel Blockersincreases risk of bradycardia.Monitor

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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).