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Nesacaine Mpf

Generic: Chloroprocaine Hydrochloride

Rx only
Local anestheticAlso: Nesacaine✓ FDA-verified
View full FDA label ↗
Nesacaine is a local anesthetic used to numb specific areas of the body during procedures, helping to block pain signals from nerves. It works by interrupting the way nerves send messages to the brain, effectively stopping the sensation of pain. The medication can be given as a single injection or through a catheter, with a starting dose of up to 11 mg per kilogram of body weight for adults, not exceeding 800 mg total, and adjustments may be needed for children or those with certain health conditions. It's important to know that Nesacaine should not be used in patients who are allergic to similar anesthetics in the PABA ester group. Additionally, caution is advised when using it with ergot-type oxytocic drugs, as this combination can lead to severe high blood pressure.
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Uses

  • Local anesthesia by infiltration.
  • Peripheral nerve block.
  • Central nerve block.
  • Lumbar epidural block.
  • Caudal epidural block.
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Dosage

Adults: 11 mg/kg without epinephrine, 14 mg/kg with epinephrine.
Maximum dose: 800 mg without epinephrine, 1000 mg with epinephrine.
Children: Maximum 11 mg/kg based on age and weight.
For caudal anesthesia: 15 to 25 mL of 2% or 3% solution.
For lumbar epidural: 2 to 2.5 mL per segment of 2% or 3% solution.
Always follow your doctor's specific instructions for your dose.
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Side effects

Common

Restlessnessanxietydizzinessblurred visionTremorsconvulsionsdrowsinessunconsciousnessHypotensionbradycardiaitchingswellingBackache and headache after lumbar or caudal block

Serious

cardiac arrestAllergic reactions: hives
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Warnings

⚠ Important warnings

  • Only use by trained clinicians.
  • Immediate availability of resuscitation equipment is necessary.
  • Do not use Nesacaine for lumbar or caudal epidural anesthesia.
  • Intra-articular infusions can cause chondrolysis.
  • Avoid intravascular injection; aspiration is required.
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Drug interactions

  • Epinephrinemay increase toxicity riskCaution
  • Ergot-type oxytocic drugsmay cause severe hypertensionCaution

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Answers pulled from the FDA label only.

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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).