Polocaine

Generic: Mepivacaine Hydrochloride

Rx only

Local anesthetic✓ FDA-verified

Polocaine is a local anesthetic used mainly for numbing during dental procedures in both adults and children. It works by blocking nerve signals in the area where it is injected, preventing pain during treatment. The medication is typically given as an injection, with a starting dose of about one cartridge (which contains either 34 mg or 51 mg of the active ingredient) and a maximum dose of up to 3 mg per pound of body weight, not exceeding 400 mg in adults. It's important to note that Polocaine should not be used by anyone who is allergic to amide-type local anesthetics. Additionally, caution is advised if you have heart conditions, as the medication can interact with certain heart medications.

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Uses

Local anesthesia for dental procedures in adults.
Local anesthesia for dental procedures in pediatric patients.

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Dosage

Dose varies based on the area and individual tolerance.

Average dose for upper or lower jaw is 1 cartridge (1.7 mL).

For the entire oral cavity, 5.3 cartridges may be needed.

Maximum dose for adults is 400 mg in one sitting.

Pediatric maximum dose is based on child's weight.

Always follow your doctor's specific instructions for your dose.

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Side effects

Common

Nervousnessdizzinessblurred visiontremorsDrowsinessPersistent numbness in lips or tongue may occur

Serious

convulsionsunconsciousnessrespiratory arrestAllergic reactions can include skin rashes or swelling

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Warnings

⚠ Important warnings

Resuscitative equipment must be available during use.
Fatal reactions can occur even without prior allergies.
Use cautiously in patients with heart disease or hypertension.
Sulfite in some formulations may cause allergic reactions.
Monitor for methemoglobinemia, especially in vulnerable patients.

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Drug interactions

Tricyclic antidepressantsmay cause severe hypertensionCaution
Monoamine oxidase inhibitorsmay lead to prolonged hypertensionCaution
Ergot-type drugsrisk of severe hypertensionCaution
Phenothiazinesmay reduce Epinephrine's effect.Caution

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Answers pulled from the FDA label only.

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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).