MedDataToolPolocaine Mpf
Generic: Mepivacaine Hydrochloride
Local anestheticAlso: Polocaine-MPF, Polocaine✓ FDA-verified
View full FDA label ↗Polocaine, which contains mepivacaine, is a medication used to numb specific areas of the body during medical procedures, providing local or regional pain relief. It works by blocking the nerves that send pain signals to the brain, effectively stopping the sensation of pain in the targeted area. The medication is given as an injection, and for most adults, the starting dose is typically around 400 mg, but it should not exceed 1,000 mg in a 24-hour period. It's important to note that Polocaine should not be used in patients who have a known allergy to it or other similar local anesthetics. Additionally, caution is advised when using it alongside ergot-type medications, as this combination can lead to severe high blood pressure.
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Uses
- Local or regional pain relief.
- Anesthesia for surgical procedures.
- Epidural and caudal blocks.
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Dosage
Adults: up to 400 mg per procedure.
Pediatric: 5–6 mg/kg based on weight.
Reduce doses for elderly or sick patients.
Avoid large volume injections; use smaller doses.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
Restlessnessanxietydizzinessblurred visionNauseavomitingchillstremorsLow blood pressureslow heart rateMethemoglobinemia causing skin discoloration
Serious
Severe allergic reactions like hives or swelling
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Warnings
⚠ Important warnings
- Only trained clinicians should use this drug.
- Risk of serious heart and breathing issues.
- Avoid in patients with certain blood disorders.
- Do not use with certain antidepressants or vasopressors.
- Not approved for intra-articular infusions.
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Drug interactions
- Monoamine oxidase inhibitorsrisk of severe hypertensionCaution
- Tricyclic antidepressantsrisk of prolonged hypertensionCaution
- Ergot-type oxytocic drugsrisk of severe hypertensionCaution
- Other local anestheticsincreased risk of methemoglobinemiaMonitor
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Answers pulled from the FDA label only.
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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).