MedDataToolPropofol is a medication used for anesthesia and sedation during surgeries or medical procedures, as well as for sedating patients in intensive care. It works by enhancing the effects of a natural calming chemical in the brain, helping to induce sleep and reduce awareness. The medication is given through an intravenous (IV) line, with the starting dose typically ranging from 2 mg to 2.5 mg per kilogram of body weight for adults, and the maximum dose should be determined by a healthcare professional based on individual needs. It's important to know that propofol should not be used by anyone who has a known allergy to it or its ingredients, especially those allergic to eggs or soy. Additionally, using propofol with other sedatives or opioids can increase the risk of breathing problems and should be closely monitored.
✦
Uses
- Induction of general anesthesia for patients 3 years and older.
- Maintenance of general anesthesia for patients 2 months and older.
- Monitored anesthesia care (MAC) sedation in adults.
- Sedation for adults with regional anesthesia.
- ICU sedation for intubated, mechanically ventilated adults.
◷
Dosage
Adults under 65: 2 mg/kg to 2.5 mg/kg for induction.
Elderly or debilitated: 1 mg/kg to 1.5 mg/kg for induction.
Pediatric patients 3 to 16 years: 2.5 mg/kg to 3.5 mg/kg for induction.
Continuous infusion for adults: 100 mcg/kg/min to 200 mcg/kg/min.
Always follow your doctor's specific instructions for your dose.
⚠
Side effects
Common
bradycardiahypotensionapnearashburning at injection sitehypersensitivity reactions
Serious
cardiac arrestrespiratory depression
🛑
Warnings
⚠ Important warnings
- Not recommended for patients under 3 years for induction.
- Not recommended for patients under 2 months for maintenance.
- Use caution in elderly or debilitated patients due to increased risks.
- Monitor for hypotension and respiratory issues after rapid administration.
- Avoid rapid bolus doses in elderly or ASA-PS III or IV patients.
⇄
Drug interactions
- Opioidsmay increase sedation and lower blood pressureCaution
- Valproatemay increase blood levels of propofolCaution
- Sedativesmay enhance sedative effects of propofolCaution
Ask about this drug
Answers pulled from the FDA label only.
Other Brands:
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).