MedDataToolSeroquel is a medication used to treat conditions like schizophrenia and bipolar disorder, including both manic and depressive episodes. It works by affecting certain chemicals in the brain that help regulate mood and thought processes. You can take it as a tablet, either with or without food, starting at a dose of 25 mg twice daily, which can be increased to a maximum of 750 mg per day for adults. It's important to know that Seroquel is not recommended for people who are allergic to it or its ingredients. Additionally, if you are taking strong medications that affect liver enzymes, like ketoconazole, your doctor may need to adjust your Seroquel dose significantly.
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Uses
- Schizophrenia.
- Bipolar I disorder manic episodes.
- Bipolar disorder depressive episodes.
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Dosage
Adults with schizophrenia: Start at 25 mg twice daily, increase to 150-750 mg/day.
Adolescents (13-17 years) with schizophrenia: Start at 25 mg twice daily, increase to 400-800 mg/day.
Adults with bipolar mania: Start at 50 mg twice daily, increase to 400-800 mg/day.
Children and adolescents (10-17 years) with bipolar mania: Start at 25 mg twice daily, increase to 400-600 mg/day.
Adults with bipolar depression: Start at 50 mg once daily at bedtime, maximum 300 mg/day.
Elderly patients: Consider starting at a lower dose and monitor closely.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
Somnolencedry mouthdizzinessconstipationweight gainIncreased mortality in elderly with dementia-related psychosis
Serious
suicidal thoughtsstroke
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Warnings
⚠ Important warnings
- Increased mortality in elderly patients with dementia-related psychosis.
- Risk of suicidal thoughts and behaviors in children and young adults.
- Not approved for treating dementia-related psychosis.
- Use caution in elderly and patients with liver impairment.
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Drug interactions
- Ketoconazolereduce quetiapine dose to one sixthCaution
- Phenytoinmay require up to 5-fold dose increaseCaution
- Divalproexmay decrease quetiapine levelsCaution
- Alcoholmay enhance cognitive and motor effects.Caution
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Answers pulled from the FDA label only.
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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).