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Tiotropium Bromide

Generic: Tiotropium Bromide And Olodaterol

Rx only
Anticholinergic and LABAAlso: Stiolto Respimat✓ FDA-verified
View full FDA label ↗
Tiotropium bromide is a medication used for the long-term management of chronic obstructive pulmonary disease (COPD), which includes conditions like chronic bronchitis and emphysema. It works by relaxing the muscles in the airways, making it easier to breathe. You take it by inhaling two puffs once a day at the same time each day, and you should not exceed this dose. It's important to know that this medication is not suitable for treating asthma or for people who are allergic to its components. Additionally, if you take certain medications like cimetidine, it may affect how tiotropium works in your body, so be sure to discuss this with your doctor.
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Uses

  • Chronic obstructive pulmonary disease (COPD).
  • Chronic bronchitis.
  • Emphysema.
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Dosage

Two inhalations of STIOLTO RESPIMAT once daily at the same time of day.
Do not exceed two inhalations every 24 hours.
For oral inhalation only.
If not used for more than 3 days, actuate the inhaler once.
If not used for more than 21 days, prime the inhaler again.
Always follow your doctor's specific instructions for your dose.
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Side effects

Common

Common side effects include nasopharyngitiscoughand back pain

Serious

Serious side effects may include worsening of narrow-angle glaucoma and urinary retention
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Warnings

⚠ Important warnings

  • Not for treating acute COPD deterioration.
  • Not for treating asthma.
  • Monitor closely for anticholinergic effects in patients with renal impairment.
  • Use caution with other adrenergic drugs.
  • Avoid with other anticholinergic medications.
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Drug interactions

  • Cimetidinemay increase tiotropium levelsCaution
  • Ranitidineno significant effect on tiotropiumCaution
  • Fluconazoleno relevant effect on olodaterolCaution
  • Ketoconazolemay increase olodaterol levelsCaution
  • Beta-blockersmay decrease effectiveness of olodaterol.Caution

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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).