MedDataToolZepbound
Generic: Tirzepatide
GLP-1 receptor agonistAlso: Zepbound KwikPen✓ FDA-verified
View full FDA label ↗Zepbound is a medication used to help adults with obesity or overweight manage their weight alongside a reduced-calorie diet and increased physical activity. It works by affecting hormones in the body that help control appetite and food intake, which can lead to weight loss. You start with an injection of 2.5 mg once a week for the first four weeks, and then the dose can be increased to a maximum of 15 mg once a week, depending on how well you tolerate it. It's important to know that Zepbound should not be used if you have a personal or family history of certain thyroid cancers. Additionally, it may affect how well other medications, especially oral ones, are absorbed, so be sure to talk to your doctor about any other medications you are taking.
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Uses
- reduce excess body weight in adults with obesity. maintain weight reduction in adults with obesity. treat moderate to severe obstructive sleep apnea in adults with obesity.
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Dosage
Start with 2.5 mg injected once weekly for 4 weeks.
Increase to 5 mg, 10 mg, or 15 mg once weekly as needed.
For obstructive sleep apnea, use 10 mg or 15 mg once weekly.
Administer at any time of day, with or without meals.
Inject in the abdomen, thigh, or upper arm, rotating sites.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
nauseadiarrheavomitingconstipationabdominal painfatiguethyroid tumors
Serious
severe gastrointestinal issueskidney injurygallbladder disease
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Warnings
⚠ Important warnings
- Risk of thyroid C-cell tumors; not for those with a history of medullary thyroid carcinoma.
- Not recommended for patients with Multiple Endocrine Neoplasia syndrome type 2.
- Caution with insulin or insulin secretagogues to avoid low blood sugar.
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Drug interactions
- Insulinmay increase risk of low blood sugarCaution
- Oral medicationsabsorption may be affected.Caution
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Answers pulled from the FDA label only.
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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).