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Cholestyramine

Generic: Cholestyramine Light

Rx only
Bile Acid Sequestrant✓ FDA-verified
View full FDA label ↗
Cholestyramine is a medication used to help lower high cholesterol levels in the blood and relieve itching caused by certain liver problems. It works by binding to bile acids in the intestines, which helps reduce cholesterol levels in the body. You typically take it as a powder mixed with water or another drink, starting with one pouch or scoop once or twice a day, and you can increase to a maximum of six pouches or scoops daily. It's important to know that this medication should not be used if you have a complete blockage of the bile ducts. Additionally, it may work better when combined with certain cholesterol-lowering medications like statins.
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Uses

  • High cholesterol.
  • Pruritus from partial biliary obstruction.
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Dosage

Start with 1 pouch or scoopful once or twice a day.
Maintenance is 2 to 4 pouches daily, divided into two doses.
Take with meals for best results.
Do not take in dry form; mix with water or fluids.
Always follow your doctor's specific instructions for your dose.
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Side effects

Common

constipationLess common: abdominal painflatulencenauseavomitingdiarrheaintestinal obstruction

Serious

vitamin deficienciesliver function abnormalities
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Warnings

⚠ Important warnings

  • Contains phenylalanine; caution for phenylketonurics.
  • May interfere with absorption of other medications.
  • Use caution in elderly patients.
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Drug interactions

  • Warfarinmay reduce its effectivenessCaution
  • Thiazide diureticsmay reduce absorptionCaution
  • Tetracyclinemay reduce absorptionCaution
  • Digitalismay interfere with its effectiveness.Caution

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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).