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Nitrofurantoin

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Nitrofuran✓ FDA-verified
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Nitrofurantoin is a medication used to treat urinary tract infections caused by certain bacteria. It works by damaging the bacteria's ability to grow and multiply. Adults typically take it in the form of a capsule or liquid, with a starting dose of 50 mg to 100 mg four times a day, and it can be taken with food to help absorption. It's important to know that nitrofurantoin should not be used if you have severe kidney problems, as this can increase the risk of side effects. Additionally, antacids containing magnesium trisilicate can reduce how well the medication is absorbed, so it's best to avoid taking them together.
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Uses

  • Urinary tract infections in adults.
  • Urinary tract infections in children 1 month and older.
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Dosage

Adults: 50 mg to 100 mg four times a day.
Children: 5 mg/kg to 7 mg/kg per day, divided into four doses.
Take with food to improve absorption.
Continue therapy for one week or at least 3 days after urine is clear.
Always follow your doctor's specific instructions for your dose.
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Side effects

Common

Nauseavomitingloss of appetitedizzinessheadache

Serious

Severe lung reactionsliver damagenerve damageallergic reactions
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Warnings

⚠ Important warnings

  • Not for treating pyelonephritis or perinephric abscesses.
  • Risk of drug-resistant bacteria if misused.
  • Monitor for signs of lung or liver issues.
  • Use cautiously in patients with kidney problems.
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Drug interactions

  • Antacidsreduces absorption of nitrofurantoinCaution
  • Uricosuric drugsmay increase toxicity and reduce effectiveness.Caution

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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).