MedDataToolNitrofurantoin Macrocrystals is a medication used to treat urinary tract infections caused by certain bacteria. It works by targeting and killing the bacteria in the urinary system. You take it in capsule form, usually 50 mg to 100 mg four times a day with food to help your body absorb it better. It's important to know that this medication should not be used if you have serious kidney problems, as it can increase the risk of side effects. Additionally, if you are pregnant at term or have a history of liver issues related to this medication, you should avoid taking it.
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Uses
- Urinary tract infections caused by E. coli.
- Urinary tract infections caused by enterococci.
- Urinary tract infections caused by Staphylococcus aureus.
- Urinary tract infections caused by certain Klebsiella strains.
- Urinary tract infections caused by certain Enterobacter strains.
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Dosage
50 mg to 100 mg four times a day for adults. 5 mg/kg to 7 mg/kg for pediatric patients, divided into four doses.
Take with food to improve absorption.
Continue therapy for one week or at least 3 days after urine is sterile.
Long-term therapy may require lower doses at bedtime.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
NauseaVomitingLoss of appetiteCoughDifficulty breathingPeripheral neuropathyDiarrhea
Serious
Severe lung reactionsLiver problemsAllergic reactions
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Warnings
⚠ Important warnings
- May cause serious lung reactions; discontinue if symptoms occur.
- Risk of liver damage; monitor liver function.
- Peripheral neuropathy may occur, especially in certain patients.
- Hemolytic anemia can occur in patients with G6PD deficiency.
- Clostridium difficile-associated diarrhea may develop.
- Not for treating pyelonephritis or perinephric abscesses.
Ask about this drug
Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).