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Nitroglycerin

Rx only
Nitrate✓ FDA-verified
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Nitroglycerin is a medication used to quickly relieve chest pain from angina, which is caused by reduced blood flow to the heart. It works by relaxing and widening blood vessels, making it easier for blood to flow and reducing the heart's workload. You take it as a tablet that you place under your tongue at the first sign of chest pain, starting with one tablet and allowing it to dissolve; you can take another every 5 minutes if needed, but no more than three tablets in 15 minutes. It's important to know that you should not use nitroglycerin if you are taking certain medications for erectile dysfunction, like sildenafil, as this can cause a dangerous drop in blood pressure. Always talk to your doctor about any medications you are taking to avoid serious interactions.

Uses

  • acute relief of angina pectoris. acute prophylaxis of angina pectoris.

Dosage

Take one tablet under the tongue at the first sign of angina.
Allow the tablet to dissolve without swallowing.
You can take one additional tablet every 5 minutes if needed.
Do not take more than three tablets in 15 minutes.
If pain continues after three tablets, seek medical help.
Can be taken 5 to 10 minutes before activities that may trigger angina.

Side effects

Common

headachedizzinessparesthesiahypotension

Serious

syncopehypersensitivity reactions
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Warnings

⚠ Important warnings

  • Do not use with PDE-5 inhibitors like sildenafil.
  • Avoid ergotamine as it may increase side effects.
  • Use cautiously in patients with low blood pressure.

Drug interactions

  • Aspirinincreased exposure to nitroglycerinCaution
  • Ergotamineincreased risk of side effectsMonitor
  • t-PAreduced thrombolytic effect.Caution

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Answers pulled from the FDA label only.

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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).