MedDataToolProgesterone is a medication used to help prevent a condition called endometrial hyperplasia in postmenopausal women who are also taking estrogen, and it can also treat secondary amenorrhea, which is when a woman doesn't have her period. It works by mimicking the natural hormone progesterone in the body, helping to balance the effects of estrogen. You take it in capsule form, usually at bedtime, starting with a dose of 200 mg for 12 days in a 28-day cycle for endometrial hyperplasia, or 400 mg for 10 days for secondary amenorrhea. It's important to know that this medication should not be used if you have a history of breast cancer or active blood clots. Additionally, if you are taking ketoconazole, a medication used to treat fungal infections, it may increase the effects of progesterone, so you should talk to your doctor about this interaction.
✦
Uses
- Prevention of endometrial hyperplasia.
- Secondary amenorrhea.
◷
Dosage
200 mg at bedtime for 12 days per 28-day cycle for endometrial hyperplasia.. 400 mg at bedtime for 10 days for secondary amenorrhea.
Take capsules with a glass of water if you have trouble swallowing.
Always follow your doctor's specific instructions for your dose.
⚠
Side effects
Common
headachebreast tendernessjoint paindizzinessabdominal bloatingincreased risk of blood clots
Serious
strokebreast cancerand dementia
🛑
Warnings
⚠ Important warnings
- Do not use to prevent heart disease, strokes, or dementia.
- Increased risk of blood clots and cardiovascular disorders.
- Monitor for signs of stroke or heart problems.
- Discuss ongoing need for treatment with your doctor regularly.
⇄
Drug interactions
- Ketoconazolemay increase progesterone levels.Caution
Ask about this drug
Answers pulled from the FDA label only.
Other Brands:
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).