Tiotropium

Generic: Tiotropium Bromide And Olodaterol

Rx only

Anticholinergic and LABAAlso: Stiolto Respimat✓ FDA-verified

Tiotropium is a medication used for the long-term management of chronic obstructive pulmonary disease (COPD), which includes conditions like chronic bronchitis and emphysema. It works by relaxing the muscles in the airways, making it easier to breathe. You take it by inhaling two puffs once a day at the same time each day, and you should not exceed this dose. It's important to note that tiotropium is not suitable for treating asthma or for people who are allergic to its ingredients. Additionally, if you're taking certain medications like cimetidine, it may affect how tiotropium works in your body, so be sure to discuss this with your doctor.

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Uses

Chronic obstructive pulmonary disease (COPD).
Chronic bronchitis.
Emphysema.

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Dosage

Two inhalations of STIOLTO RESPIMAT once daily at the same time of day.

Do not exceed two inhalations every 24 hours.

For oral inhalation only.

If not used for more than 3 days, actuate the inhaler once.

If not used for more than 21 days, prime the inhaler again.

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Side effects

Common

Nasopharyngitiscoughback painImmediate hypersensitivity reactions

Serious

worsening of narrow-angle glaucomaworsening of urinary retention

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Warnings

⚠ Important warnings

Not for treating acute COPD deterioration.
Not for treating asthma.
Monitor closely for anticholinergic effects in patients with moderate to severe renal impairment.
Use caution with other adrenergic drugs.
Avoid with other anticholinergic medications.

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Drug interactions

Cimetidineincreases tiotropium levelsMonitor
Ranitidineno effect on tiotropiumCaution
Fluconazoleno effect on olodaterolCaution
Ketoconazoleincreases olodaterol levelsMonitor
Beta-blockersmay decrease effectiveness.Caution

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Answers pulled from the FDA label only.

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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).