MedDataToolQuetiapine is a medication used to treat conditions like schizophrenia and bipolar disorder, including both manic and depressive episodes. It works by helping to balance certain chemicals in the brain that affect mood and behavior. You can take it as a tablet, either with or without food, starting at a dose of 25 mg twice daily for adults, with a maximum dose of 750 mg per day. It's important to know that quetiapine should not be taken if you have a known allergy to it or any of its ingredients. Additionally, if you are taking strong medications that affect liver enzymes, like ketoconazole, your doctor may need to adjust your quetiapine dose significantly.
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Uses
- Schizophrenia.
- Bipolar I disorder manic episodes.
- Bipolar disorder depressive episodes.
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Dosage
Adults: Start at 25 mg twice daily for schizophrenia, adjust to 150–750 mg daily.
Adolescents (13-17 years): Start at 25 mg twice daily for schizophrenia, adjust to 400–800 mg daily.
Adults: Start at 50 mg twice daily for bipolar mania, adjust to 400–800 mg daily.
Children (10-17 years): Start at 25 mg twice daily for bipolar mania, adjust to 400–600 mg daily.
Adults: 50 mg once daily at bedtime for bipolar depression, adjust to 300 mg daily.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
Somnolencedry mouthdizzinessconstipationweight gainIncreased mortality in elderly with dementia-related psychosis
Serious
suicidal thoughtsstroke
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Warnings
⚠ Important warnings
- Increased mortality in elderly patients with dementia-related psychosis.
- Risk of suicidal thoughts and behaviors in children and young adults.
- Not approved for use in pediatric patients under ten years of age.
- Monitor closely for worsening symptoms.
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Drug interactions
- Ketoconazoleincrease quetiapine levels significantlyCaution
- Phenytoinincrease quetiapine clearance significantlyCaution
- Divalproexmay decrease quetiapine levels slightly.Caution
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Answers pulled from the FDA label only.
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Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).