MedDataToolSitagliptin is a medication used to help manage blood sugar levels in adults with type 2 diabetes when combined with a healthy diet and exercise. It works by increasing the levels of certain hormones in your body that help control insulin and blood sugar levels after meals. You typically take it as a pill once a day, starting with a dose of 100 mg, which can be adjusted to 50 mg or 25 mg if you have kidney problems, but you should not exceed 100 mg daily. It's important to know that sitagliptin should not be used if you have a history of serious allergic reactions to it. Additionally, if you are taking insulin or certain other diabetes medications, you may need to be cautious about the risk of low blood sugar.
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Uses
- Type 2 diabetes mellitus.
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Dosage
100 mg once daily.
Can be taken with or without food.
For moderate renal impairment, 50 mg once daily.
For severe renal impairment, 25 mg once daily.
Always follow your doctor's specific instructions for your dose.
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Side effects
Common
Upper respiratory tract infectionNasopharyngitisHeadacheHypoglycemia when used with insulinPancreatitis
Serious
Severe allergic reactions
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Warnings
⚠ Important warnings
- Not for patients with type 1 diabetes.
- Not studied in patients with pancreatitis history.
- Risk of pancreatitis is unknown.
- Monitor renal function before and during treatment.
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Drug interactions
- Insulinmay require lower doses to prevent hypoglycemiaCaution
- Sulfonylureamay require lower doses to prevent hypoglycemiaCaution
Ask about this drug
Answers pulled from the FDA label only.
Medical Disclaimer: This content is provided for informational and educational purposes only and is not intended as medical advice. Always consult a qualified healthcare provider before taking any medication.
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).
Data Source: Publicly available drug labeling information from the U.S. Food and Drug Administration (FDA).